Our state-of-the-art AI, fine-tuned on diverse biological samples, delivers high-fidelity segmentation of individual cells or fibers. It excels even in noisy, complex human tissue where other automated tools fail.
We extract a rich set of morphological features for every single object—size, area, circularity, myelin thickness, G-ratio, and more. We turn your image from a picture into a powerful, high-dimensional dataset ready for analysis.
This is where we go beyond. We pioneer the use of advanced spatial statistics like Voronoi tessellation and Delaunay triangulation to map the "rules" of your tissue's organization. By combining these spatial metrics with morphometrics, we create a holistic "architectural fingerprint"—a powerful, custom Pathological Index for your specific research question.
We provide an end-to-end solution that extracts unprecedented levels of data from any segmentable tissue image. Wherever there is a structure to analyze, we can build a quantifiable index of its pathological state. This analytical bottleneck means critical architectural information hidden within your images remains untapped, slowing down research and the development of new diagnostics. It's time for a new paradigm.
We applied our platform to one of the most complex challenges in neuro-pathology. The results not only revealed new disease mechanisms but also produced a novel diagnostic biomarker. In a large-scale study, we analyzed over 23,000 individual myelinated nerve fibers across 45 human and mouse samples, discovered a new disease paradigm: a dual pathology of profound whole-nerve atrophy (46% smaller than healthy nerves) and a degenerative reversal of fiber populations.
Our framework is a versatile discovery engine, validated across diverse biological challenges. We empower researchers in any field where tissue architecture matters. Developed a novel Pathological Index: The "Neuropathy Index" synthesizes these multi-scale findings into a single metric with good diagnostic performance (AUC = 0.822) for identifying diseased nerves. This is our blueprint: we turn complex pathology into a quantifiable, diagnostic metric.
Our framework is a versatile discovery engine, validated across diverse biological challenges. We empower researchers in any field where tissue architecture matters.
View AllInvestigating nerve fiber distribution and morphology to advance understanding of peripheral nerve disorders.
Analyzing tissue organization and cellular patterns during embryonic development and organogenesis.
Quantifying cellular features in clinical samples to identify biomarkers and support translational research.
We work with you to understand your research questions and define the specific metrics and biomarkers most relevant to your study
Our AI pipeline performs high-fidelity segmentation and extracts comprehensive morphometric data from your tissue images
Receive comprehensive reports with statistical analyses, visualizations, and raw data exports ready for publication
Journal: The Journal of Physiology (2025)
Authors: Moore W, Nikesjö J, Bouchatta O, Makdani AD, Hakizimana P, Rousson M, Duvernoy B, McIntyre S, Pehkonen LJ, Fridberger A, McGlone F, Olausson H, Nagi SS, Marshall A.